2011年7月26日 星期二

Neuroendocrine modulation of cancer progression

Guillermo N. Armaiz-Pena , Susan K. Lutgendorf , Steve W. Cole , Anil K. Sood

abstract

Clinical and animal studies now support the notion that psychological factors such as stress, chronic depression, and lack of social support might promote tumor growth and progression. Recently, cellular and molecular studies have started to identify biological processes that could mediate such effects. This review provides a mechanistic understanding of the relationship between biological and behavioral influences in cancer and points to more comprehensive behavioral and pharmacological approaches for better patient outcomes.

中文摘要:
臨床及動物之研究支持下面之觀點:即心理因素諸如壓力長期憂鬱及缺乏社會支持皆可增加腫瘤之生長及發展。最近,細胞學及分子之研究開始指出哪些生物過程可以產生這些效果。本論文提出一個能影響癌症進度之生物及行為表現機制,併指出一些是病人能有所改善之行為及藥物方法。



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